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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name ILK siRNA
ncRNA Category siRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line HXO-Rb
Methods siRNA transfection, RT-PCR, Western blot, CCK-8 assay, Annexin/PI double immunofluorescence, flow cytometry
Expression pattern associated
Functional description ILK siRNA can downregulate the expression of ILK gene in HXO-Rb(44) cells inhibited the cell proliferation and induced their apoptosis.
PubMed ID 22490953
Year 2012
Title siRNA-mediated downregulation of the integrin-linked kinase alters the proliferation and apoptosis in retinoblastoma cells.
Drug-related ncRNA NO

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